AP23488960 «Development of technology for the production of new cosmeceutical products based on domestic natural raw materials»

2024-2026 36 month SDG #12 SDG #12

Project Leader

Mussabayeva Binur Khabasovna, Candidate of Chemical Sciences, Professor

Relevance

The lack of domestic manufacturers of cosmetic products in the market of Kazakhstan. The presence of medicinal natural mud, brine, wild medicinal plants and animal products in the territory of Eastern Kazakhstan, the properties of which have not been previously studied for the possibility of use in cosmetic products. The prospect of developing a technology for new cosmeceutical products with the processing of medicinal mud, animal products and medicinal plants.

Goal

Development of a technology for the production of cosmeceutical products with the presentation of prototypes based on physical, chemical and biological studies of samples of medicinal mud from Eastern Kazakhstan and the selection of natural additives from fermented milk products, fats and plant extracts.

Expected Result

samples of medicinal mud, medicinal plants, and animal products will be selected and examined for suitability for cosmeceutical products.

cosmeceutical compositions will be made from natural raw materials, and their stability will be studied.

stable compositions will be tested on skin models.

At least 5 prototypes of samples of cosmeceutical products based on therapeutic mud and natural additives will be presented.

a technological scheme of production will be developed to obtain the necessary parameters for drawing up a Business plan for future production.

Achieved Result

Cosmetologist's compositions on the basis of medical products and natural products: five compositions of creams, two compositions of masks, two compositions of scrubs, shampoos and masks. In the quality of natural products used extracts of various medicinal substances, lanolin and lyophilized cumysa. The standards are standardized, which includes a passport for security. The developed compositions are protested in Model conditions, as well as in the conditions of employment and living.

The results of the application of developed compositions for morphometric characteristics in different model conditions were obtained. Annotated report / promzhutochny report. 2 patents of the Republic of Kazakhstan on a polesical model, Published 1 article in peer-reviewed scientific research, which has a percentile on CiteScore in base Scopus 90 (devyanosta), 1 appearance/publication in SMI.

- Cosmetological compositions protested in the University of Adama Mickiewicz G. Poznani, Poland in Model facilities on instruments:

1) Tewameter® TM 300 (for determination of the transepidermal surface of water, TEWL),

2) Corneometer® CM 825 (skin hydration),

3) Visioscan® VC 98 (parameters of the relief of the body: SEr - sheariness, SEsm – gladness, SEsc – cheshuychateness, SEw – burrs).

2 protest compositions of scrubs showed a good effect and significantly reduced the efficiency of the body. 2 compositions of masok showed a good effect of lifting tons of Kozhi, in a different step to increase efficiency and sheltering Kozhi. The results of testing in Model conditions of scrubbing and masok are evaluated.

- Cosmetological compositions of creams protested in vivo for living and well-being (the conclusion of the ethical commission was received):

1) the study of living (white blood cells) was conducted in the laboratory – vivari NAO "Semey Medical University". For living, there was a growing and counterproductive activity of cream compositions with the content of 7% of lipid extracts of lecithin, as well as a regenerative activity of cream compositions with the content of 10% of corrosive extracts.

2) testing for the recipients of the information received was carried out with the permission of the ministry. The test showed the elimination of irritating and allergic reactions to the composition (the act of destruction was concluded).

- 2 patents of the Republic of Kazakhstan on the field model:

1) Kazhygeldieva L. K., Musabaeva B. K., Sabitova A. N., Silybaeva B. M., Orazzhanova L. K. patent of the Republic of Kazakhstan on the field model "Lotion for stimulating the growth of Volos" No. 10435.date Reg. 18.04.2025.

2) Akimzhanova H. G., Sabitova A. N., Musabaeva B. H. patent of the Republic of Kazakhstan on the field model "assistance in obtaining lipids from medical products". No. 10827. date Reg. 04.07.2025.

- The article is published in reference to the percentage of CiteScore in base Scopus 90

(https://www.scopus.com/sourceid/21101039622):

Mussabayeva B., Akimzhanova K., Sabitova A., Ydyrys A., Kruszka D., Cerazy-Waliszewska J., Łęska B., Tabisz L. Extraction of Lipids from Natural Saline Mud and their Interpretation from Point of Biological Activity in the Context of Salt Lakes of North-East Kazakhstan // Engineered Science. 2025. 36:1628. DOI: 10.30919/es1628

Published: July 18, 2025

- The article is published in domestic scientific research, recommended by KOKNVO:

Kazhygeldiyeva L.K., Mussabayeva B.Kh., Sabitova A. N., Orazzhanova L.K., Seitkan A.S. Determination of the Chemical Composition and Antioxidant Activity of Fruit Extracts From Hippophae Rhamnoides L. and Crataegus Sanguinea L.// News of the National Academy of Sciences of the Republic of Kazakhstan. Series Chemistry and Technology. - 2025. - V. 462 (1). - P. 68-78.

https://doi.org/10.32014/2025.2518-1491.267

Published: March, 2025.

- Results of the International Conference:

Sabitova A., Akimzhanova K., Mussabayeva B. The chemical and mineralogical composition of the natural black mud of the East Kazakhstan lakes // IX Congreso Iberoamericano de Peloides, Balneario de Arnedillo, La Rioja, Spain, May 7-9, 2025. – P. 105-109.

https://www.termaeuropa.com/recursos/novedades/fichero57.pdf.

- In the social network shakarim_university published a video on the implementation of the scientific project "Shakarim University creates new medical cosmetics":

https://www.instagram.com/reel/DF964rINTm2/?igsh=cDNhcDhpNnlzaGp4