AP22686900 "The effective methods of treatment and prevention of strongylatous-trichocephalous-eimeric invasion of sheep"
Project Leader
Akhmetzhanova Aizhan Yerkingazievna, Acting Associate Professor, PhD
Relevance
Abay region is considered to be the largest sheep breeding region in Kazakhstan. A huge area of pastures and an abundance of forage resources allow to develop sheep farming greatly in the region. However, the increase in the number of sheep, the quality of products obtained from them, as well as the economy of the region as a whole are affected by frequent invasive diseases of sheep. The lack of intensive development of animal husbandry is also influenced by the ineffectiveness of the fight against invasive animal diseases. As a fact several pathogens live in the animal's body at the same time, including helminths and protozoan parasites. They affect about 80% of sheep. Compared with ascarids found in the nervous system, muscles and lungs of sheep, the number of roundworms that are found in the digestive organs of animals is greater and their harm is enormous.
Goal
To study the epizootology of strongylato-trichocephalous-eimeriosis infestation of sheep in sheep farms located in the radiation-hazardous territories of the former Semipalatinsk test site in the Abay oblast and to search for innovative methods of their treatment and prevention, to determine the quality of meat of sheep affected by mixed invasion.
Expected Result
The determination of the radiation background of sheep farms located in the radiation-hazardous territories of the former Semipalatinsk test site in the Abay region, the determination of the type and dynamics of the spread of strongylatosis-trichocephalosis-eimeriosis infestation of sheep in sheep farms, and creation of a geographic information system. Veterinary and sanitary studies of the quality of meat of sheep infected with strongylate trichocephalosis-eimeriosis invasion were carried out, as a result of which several new anthelmintic and anti-eimeriosis compositions were developed against associative invasion of sheep. In order to treat and prevent strongylat-trichocephalous-eimeriosis infestation in sheep, based on the results of the study, a scientific proposal was made to the sheep farm. Based on the results obtained within the framework of this project, at least 2 (two) articles will be published in journals included in the first three quartiles of the impact factor in the Web of Science database or in journals with a percentile of at least 50 according to CiteScore in the Scopus database .
Achieved Result
From January to June, a total of 200 heads of feces were brought from the farm "Zhalgas" of aksuat district, from the farm "Azbergen" of Abay district, depending on the age characteristics of sheep, and a helminthovoscopic study was carried out in the laboratory of Parasitology of the Department of Veterinary Medicine.
Broad-spectrum antiparasitic drugs have been developed and tested on clinical animals
Tests were carried out on sheep on farms in Abay district
The developed antiparasitic composition was studied for anthelmintic activity. We gave it 4 tablets (2.0 g of granules) per 20 kg of live weight of sheep in a single dose without the use (not required) of a pre-fasting diet and laxative drugs.
As a result of the study of the activity of broad-spectrum antiparasitic drugs for sheep against pinworms, the prevalence of infestation after the use of antiparasitic veterinary formulations for 30 heads of infested sheep decreased from 69.75% to 12%, in the farm "Zharkas" Tarbagatai district-from 73.75% to 11%.
A scientific article has been submitted in accordance with the project theme. Based on the results of the research conducted within the framework of the project, one article has been prepared and submitted for publication; it is currently under peer review in the international journals Acta Veterinaria Brno (Czech Republic) and Veterinarija ir Zootechnika (Lithuania).
Journal Metrics: CiteScore (2024): 0.2, Quartile Q3/Q4, Percentile 65.
Article Title: "Comparative Efficacy of a New Antiparasitic Veterinary Composition Against Gastrointestinal Helminths."
Authors: A. Akhmetzhanova, S. D. Dyusembayev, S. D. Tusupov, A. B. Myrzhiyeva, A. B. Zheksenayeva, Sh. K. Suleimenov.
Useful Links
About the project
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Contact
Scientific Department:
+7 (7222) 31-31-75
science@shakarim.kz